“Uric Acid Lowering Therapy”…You Mean “Drugs”?

Check out this article I found about uric acid lowering therapy or therapies. Basically they’re saying the drugs don’t work…they should have just asked me, I could have told them why.

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“The Majority of Gout Patients on Uric Acid Lowering Therapy Fail to Achieve Control of Serum Urate Levels Despite the Availability of Newer Treatment Options Such as Takeda’s Uloric, Menarini/Ipsen’s Adenuric and Savient Pharmaceuticals’ Krystexxa

EXTON, Pa.– (BUSINESS WIRE) –Nov 29, 2011 – Rheumatologists and Primary Care Physicians (PCP’s) in the U.S. and Europe recognize the importance of tight uric acid control as a strategy to minimize gout flares. However, despite physicians’ emphasis on using uric acid lowering (UAL) therapies to reach therapeutic levels, the majority of gout patients have serum uric acid (SUA) levels above the therapeutic target of 6.0mg/dl. The findings come from two recent reports by BioTrends Research Group, ChartTrends®: Gout U.S. and ChartTrends®: Gout Europe in which over 2,500 gout patient charts were analyzed.


Allopurinol remains the predominant first-line UAL agent of choice among PCPs and rheumatologists, although Uloric/Adenuric (febuxostat) is making inroads, particularly in the more severe gout patients. The 300mg dose of allopurinol is still the most commonly prescribed strength in both markets and many physicians are reluctant to escalate allopurinol doses due to concerns regarding the patient’s renal function and tolerability. Doses of Uloric in the U.S. were significantly higher compared to the same period last year and, among rheumatologists, doses of Adenuric in the EU are significantly higher than those in the U.S. for both moderate and severe patients.”

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Uric Acid Lowering Therapy…What Am I Missing Here?

Aren’t they just saying “stick your head in the sand” and ignore common sense? Forget the basic tenets of good health, just take drugs? Is that “uric acid lowering therapy”? Is there something wrong with me? Are they actually saying, “eat trash and live like a fool”?  Then take these pills when you get a gout attack?

Is it just me or is it really so difficult to read between the lines here? Let’s let every one think that it’s OK to eat these denatured, processed foods, and watch TV every night.  All that instead of exercising.  All the while, stressing out trying to make the car payment and the house payment every month.  Generally the message is, ignore your health.  But, if you just take this little pill you’re going to be just fine. Really? This little pill passes for “uric acid lowering therapy”?

Isn’t it a little late for therapy? Maybe if the patient had been breathing fully and completely, drinking really good water, and eating real, live foods, and managing their emotions well in the first place, they would have avoided the problem altogether. Why didn’t anybody put some money into that type of education? For the pharmaceutical companies, uric acid lowering therapy comes down to one thing: making money…and there’s no money in healthy people.

Here’s the line I liked best from the article:

  • “In the U.S. audit, patient profiles revealed that Uloric and Krystexxa patients tend to have greater disease severity with polyarticular tophi, greater likelihood of kidney damage, and a greater frequency of acute gout flares, emergency room visits and hospitalizations compared to allopurinol patients.”

Sell your Savient and Takeda stock!

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Hi Bert

Well it is more than a year since you have guided me. Yes, I’m still here and haven’t missed one of your 365 messages.

It’s been quite a journey. I’ve learnt a lot.

Time for me to say thanks for your help, concern and encouragement.
I still live in fear of another attack, however I’ve had a really good year. had a problem on my cruise last year July, and A couple of small attacks since, and funny enough they have show as sprained ankle ones, not the toes. Anyway with the Gout Killer formula and some medication they have been short lived.
I have decided not to go on permanent medication.

My lifestyle has changed in the last couple of years as mentioned before. Good breathing [ thanks to you ],
good water , a LCHF [ low carb high fat } WOE { way of eating } not much alcohol { I think alcohol can be a major problem } life is pretty good for a 73 year old.

I had a look at my Urate readings over the last 15 years, yes I have records.

They have been as low as .40 mmol/l – to .51 mmol/l average around .47 .48 .49 mmol/l. This is Australian readings, I think you use mg/dl so say around 8.5 mg/dl, if I’m correct. Yes this seems high , Aussie recommended is .12 – 0.45 mmol/l USA I think is 3.5 – 7.2 mg/dl.

Well hope that helps, don’t really know how to reduce it. Yes, I eat a lot of meat, but no seafood, or high purine meats.

We leave for Canada, Alaska and USA tomorrow, will see how I go , hope to have a few drinks, keep your fingers crossed, no, I don’t drink much beer, and all spirits are with soda water and lime. My PH is good, some what Ketogenic and only take Warfarin as a medication for a genetic blood disorder, nothing else.
BP is good , Cholesterol, triglycerides, HDL, LDL all good. Not over weight.

Keep up the good work. Still enjoy hearing from you.

Must fly, lol, literally in a few hours, will be away for 2 1/2 months.

Enjoy your summer, don’t think we will get to Colorado this time.

Dave From Downunder.

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   Remember!  Eat right & exercise: the best uric acid lowering therapy.


Bert Middleton

“I know your pain. Let me help you kill your gout for good!  And teach you to advocate for yourself and take ownership of your gout recovery, by showing you how to live the gout-free lifestyle.” Two decades ago, Bert Middleton found himself diagnosed with gout. Like 8.3 million other people in the United States (approximately 4% of the population), he struggled helplessly with the physical, emotional, social, and financial impact that gout left unchecked can have on your life. Prescription drugs were of limited help… And the terrible pain of regular gout attacks left him unable to enjoy even the simplest daily pleasures. His marriage was suffering. His finances were spiraling due to the impact gout had on his ability to work. And maintaining a social life was often nearly impossible. Tophi surgeries left him in terrible pain.  And he found himself depressed … and angry … that gout was stealing years of his life.

Until one day, after hundreds of hours of research and self-experimentation, Bert finally had a breakthrough and created a blueprint for a way of living that would prove to be “the answer” to living gout-free for nearly a decade now. Today, Bert and his “Gout Wife” Sharon devote their evenings and weekends to educating other gout sufferers on how to live the gout-free lifestyle. Showing others his 911 Emergency Response Gout Recovery Plan for getting PAINFUL gout attacks under control in as little as 4 hours. And then, how to make daily choices that keep gout under control for GOOD! So you can finally start LIVING again!